An organized 3D in vitro model for peripheral nerve studies
نویسنده
چکیده
.................................................................................................................................... 1 Presentations and publications ............................................................................................... 2 Oral presentations ...................................................................................................................... 2 Poster presentations ................................................................................................................... 3 Publications ................................................................................................................................ 3 Acknowledgements .................................................................................................................. 4
منابع مشابه
Use of Chitosan Conduit for Bridging Small-Gap Peripheral Nerve Defect in Sciatic Nerve Transection Model of Rat
Objective-To evaluate effect of chitosan conduit for peripheral nerve regeneration using sciatic nerve transection model in rat Design- Experimental in vivo study. Animals- Sixty healthy male Wistar rats. Procedures-The rats were divided into four experimental groups (n=15) randomly. In sham group the left sciatic nerve was exposed through a gluteal muscle incision and after careful...
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Introduction: The present study aims to evaluate the Three-Dimensional Diffusion-Weighted reversed fast imaging with steady state free precession (3D DW-PSIF) sequence with respect to imaging of the peripheral nerves; the tibial, medial, and lateral plantar nerves in the lower extremity, ulnar and median nerve in the upper extremity, sciatic nerve, brachial plexus, and lumbosacral plexus, and a...
متن کاملEffect of Local Administration of Laminin and Fibronectin with Chitosan Conduit on Peripheral Nerve Regeneration: A Rat Sciatic Nerve Transection Model
Objective-Effect of local administration of laminin and fibronectin on nerve regeneration was assessed. Design- Experimental study. Animal- Sixty male Wistar rats. Procedures- The animals were divided into four experimental groups (n=15), randomly: In transected group left sciatic nerve was transected and stumps were fixed in adjacent muscle. In treatment group (CHIT/LF) the defect was bridg...
متن کاملDevelopment of an advanced 3D-engineered neuronal cell culture as a screening tool for drugs promoting peripheral nerve regeneration
INTRODUCTION: Injuries associated with peripheral nerve damage effect ~1 million patients per year. Damage to the peripheral nervous system can be extremely debilitating and result in loss of end organ function, coupled with poor neuron regeneration capacity [1]. Currently the treatment option for injuries are microsurgical and there are no drug therapies available to improve recovery. Pharmaco...
متن کاملThe effect of ubiquinone on functional recovery and morphometric indices of sciatic nerve regeneration
A common cause of peripheral nerve injury is trauma. The positive effect of antioxidants on the improvement of nerve regeneration has currently become a focus of attention. In this experiment, the effect of intraperitoneal administration of ubiquinone (CoQ10) on an acute experimentally sciatic nerve crush was studied in a rat model. Forty-five male Wistar rats, weighing between 160-180 g were u...
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